Dermatopathology is not simply a laboratory test, but a consultative service to the referring dermatologist.
The pathologist interpreting these boipsies is a critical part of your health care team.
The accurate diagnosis of your patient’s tissue biopsy is absolutely essential to the selection of the most appropriate treatment plan for your patient.
One of the greatest challenges of dermatopathology is the sheer volume of different skin diseases.
There are an estimated 1,500 different rashes and skin tumors.
Therefore, dermatology and dermatopathology are among the most complex specialties of medicine.
01. Direct immunofluorescence where antigens of interest have been bound in vivo by immunoglobulins with sampling of the skin.
02. Indirect immunofluorescence where blood is taken to determine circulating antibodies to antigens of interest.
DIF is useful in the diagnosis of suspected autoimmune disease, connective tissue diseases and vasculitis. The staining patterns seen in tissue samples may be specific to a disease or may need to be interpreted with the clinical and histological findings.